HU-210 Synthetic Cannabinoid (Analytical Reference Standard)

HU 210 powder for sale! HU-210 (11-hydroxy-Delta 8 -THC-dimethylheptyl) is a synthetic analogue of Delta 8-tetrahydrocannabinol (Delta 8 -THC) belonging to the classical dibenzopyran structural class. First synthesized in 1988 under the direction of Dr. Raphael Mechoulam at the Hebrew University of Jerusalem (from which the prefix “HU” originates), HU-210 remains one of the most widely studied reference standards in cannabinoid pharmacology and neurobiology.

Unlike natural phytocannabinoids that function as partial agonists at central nervous system targets, HU-210 acts as an ultra-high-affinity full agonist at both human cannabinoid CB1and CB_2 receptors:

• CB1 Receptor Affinity(K_i): Approximately 0.06 nM, demonstrating binding efficiency up to 800 times greater than natural Delta 9-THC (K_i \approx 40.7 nM.

• CB2 Receptor Affinity(K_i) : Approximately 0.52 nM, providing high potency for peripheral receptor mapping and immune system pathways.

Catalog ID: REF-HU210-98

Chemical Class: Classical Dibenzopyran Cannabinoid Agonist

Purity Standard: greater than 98.0% (HPLC / NMR Verified)

Form: Crystalline Solid / Analytical Standard Solution

When was HU-210 first tested

HU-210 was first synthesized and tested in 1988 by a research team led by Dr. Raphael Mechoulam at the Hebrew University of Jerusalem.

The compound was first evaluated in 1988 animal studies (published in the journal Experientia in September 1988) to test the stereospecificity of its psychoactive and pharmacological effects. Follow-up behavioral and receptor binding tests in mice, dogs, pigeons, and rats were conducted shortly after in 1989. HU 210 powder for sale near me.

Early Test Highlights (1988–1990)

• Initial 1988 Screening: Researchers tested the enantiomers of 11-hydroxy- Delta 8 -THC-dimethylheptyl to observe how enantiomeric structure impacts central nervous system activity. They discovered that the  (-) enantiomer (HU-210) was extremely potent, whereas the (+) enantiomer (HU-211) lacked typical cannabinoid activity.

• 1989 In Vivo Studies: Tests conducted by Little et al. and Järbe et al. evaluated HU-210 in mice, dogs, and rats, confirming it was between 100 to 800 times more potent than natural  Delta 9 -THC in producing classic cannabinoid behavioral responses.

• 1990 In Vitro Binding Tests: Howlett et al. formally mapped HU-210’s affinity at cannabinoid receptors, demonstrating its function as an ultra-high-affinity full agonist at  CB _1 targets. HU 210 powder for sale online at Herbal spice shop

Primary Research & Analytical Applications

Due to its high stability and binding efficacy, HU-210 is widely utilized by academic institutions, forensic toxicology laboratories, and pharmaceutical research teams for:

1. Radioligand Binding Assays: Serving as a high-affinity benchmark ligand to characterize novel receptor agonists and antagonists.

2. Receptor Functional Mapping: Investigating intracellular signal transduction pathways, including G-protein coupling and adenylate cyclase inhibition.

3. Forensic Identification & Chromatography: Functioning as a certified reference material for high-performance liquid chromatography (HPLC), mass spectrometry (GC-MS / LC-MS/MS), and nuclear magnetic resonance (NMR) analytical calibration.

4. Neuroprotection Research: Evaluating receptor-mediated pathways linked to neuroinflammation and excitotoxicity models in vitro.

Chemical Profile & Physical Specifications

Parameter	Specification
IUPAC Name	(6aR,10aR)-3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-6H-dibenzo[b,d]pyran-9-methanol
CAS Registry Number	112830-95-2
Molecular Formula	C25\H38\O3
Molecular Weight	386.57  g/mol
Physical Appearance	Off-white to pale yellow crystalline solid
Purity Grade	greater than 98.0% certified purity
Solubility	Soluble in organic solvents (DMF, DMSO, Ethanol (10  mg/mL); practically insoluble in water

Quality Assurance & Storage Guidelines

Every batch of HU-210 supplied by Herbal Spice Shop is factory-sealed under an inert argon environment to prevent oxidative degradation. Each shipment includes a comprehensive batch-specific Certificate of Analysis (CoA) detailing HPLC purity analysis, mass spectra data, and storage parameters.

• Storage Conditions: Store in the original sealed container in a desiccated environment protected from direct light and moisture.

• Solvent Handling: When reconstituting in stock solutions (e.g., ethanol or DMSO), purge the container headspace with nitrogen or argon and store .

STRICT RESEARCH & LABORATORY DISCLAIMER

HU-210 is supplied exclusively for legitimate laboratory research, analytical reference testing, and scientific evaluation. It is NOT intended for human or veterinary use, clinical trials, cosmetic applications, or household consumption. Handle strictly in accordance with institutional biosafety guidelines, wearing appropriate personal protective equipment (PPE).

Why Source HU-210 Standard From Herbal Spice Shop?

When acquiring certified research standards, accuracy and logistics reliability are non-negotiable. At Herbal Spice Shop, we combine technical product standards with an efficient, buyer-focused fulfillment workflow:

• Factory-Sealed Integrity: Supplied in moisture-barrier glass vials to ensure long-term chemical stability without contamination.

• 100% Plain & Discreet Packaging: All orders are shipped in unmarked, durable outer packaging with no external references to compound names or store branding.

• Rapid 24–48 Hour Dispatch: Fast processing with full end-to-end tracking provided immediately upon shipment.

• Guaranteed Delivery Policy: In the event of an internal fulfillment error or transit issue on our end, we offer immediate, zero-cost re-shipments of replacement reference standards.

Frequently Asked Questions 

How is HU-210 classified in comparison to other synthetic cannabinoids?

HU-210 is categorized as a classical cannabinoid because its dibenzopyran core structure directly mirrors natural phytocannabinoids like Delta 8 -THC and  Deltav 9 -THC, unlike non-classical cyclohexylphenols (CP series) or indazole-3-carboxamides (5F-ADB, MDMB-4en-PINACA).

What analytical documentation is provided with my order?

Every order of HU-210 includes a batch-matched Certificate of Analysis (CoA) featuring HPLC purity verification and mass spectrometry characterization, alongside safety handling documentation (MSDS/SDS).

How is the chemical packaged to prevent transit degradation?

HU-210 is package in amber glass vials seal under an inert gas atmosphere and house inside moisture-barrier secondary packaging to protect against light exposure, oxidation, and temperature fluctuations during transit.

Can individuals purchase HU-210 for personal use?

YES. Although HU-210 is under strict restrictions to valid scientific research, educational study, and forensic identification. Orders intend for personal use or non-laboratory applications will be cancele.

Order Certified HU-210 Reference Standards Online

Secure high-purity HU-210 analytical standards directly through Herbal Spice Shop. Benefit from volume pricing options, encrypted checkout, and fast, discreet delivery directly to your facility.